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Author  |
Ra Yoon, M.; Hyun Nam, S.; Young Kang, M. |
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Title |
Antioxidative and antimutagenic activities of 70% ethanolic extracts from four fungal mycelia-fermented specialty rices |
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Journal Article |
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Year |
2008 |
Publication |
Journal of Clinical Biochemistry and Nutrition |
Abbreviated Journal |
J Clin Biochem Nutr |
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Volume |
43 |
Issue |
2 |
Pages |
118-125 |
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Abstract |
The health-promoting potential of 70% ethanolic extracts of 4 rice varieties fermented with Monascus ruber, Phellinus linteus, Cordyceps sinensis and Agaricus blazei was evaluated mainly focusing on their antioxidative and antimutagenic capacities based on the following parameters: phenolic compound and phytic acid content; inhibitory activity on lipid peroxidation; scavenging activity on DPPH radical; suppressing ability on mitomycin C-induced mutagenesis in E. coli cells; and protective effect on 4-nitroquinoline oxide-triggered DNA lesion in V79 hamster cells. The fermented rice extracts were superior in overall health-promoting parameters compared to the source material. The higher antimutagenic activity of the fermented rice extracts might be in part caused by a larger amount of antioxidant constituents such as phenolic compounds or phytic acid. Of the fungal species, Monascus ruber was found to impart a marked increase in both the antioxidative and antimutagenic abilities to the source material. The current study suggests a possibility that such fermented rice may contribute to the prevention of lifestyle-related diseases such as cancer through a daily intake of rice-based diets. |
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Address |
Department of Food Science and Nutrition, Kyungpook National University, 1370 Sankyuk-dong, Puk-gu, Daegu 702-701, Korea |
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Language |
English |
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ISSN |
0912-0009 |
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Notes |
PMID:18818745 |
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no |
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Call Number |
refbase @ user @ |
Serial |
19 |
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